La Dra. Karla Saavedra Rodriguez obtuvo su licenciatura en Biología en la Facultad de Ciencias Biológicas de la UANL en 1998; Maestría en Ciencias con Especialidad en Entomología Médica por la Facultad de Ciencias Biológicas de la UANL en 2004; Doctorado en Ciencias con especialidad en Entomología Médica por la Facultad de Ciencias Biológicas de la UANL en 2008. Es Investigador Científico de tiempo completo en Colorado State University en Fort Collins, Colorado, E.U.A. desde el 2013.  Su trabajo en investigación involucra el estudio de las bases genéticas de la resistencia a insecticidas y genética de poblaciones en artrópodos vectores de enfermedades.

Correo institucional: This email address is being protected from spambots. You need JavaScript enabled to view it.

ORCID ID: https://orcid.org/0000-0001-8511-3327

ResearchGate: https://www.researchgate.net/profile/Karla_Saavedra-Rodriguez

Artículos de investigación

2020

Vera-Maloof FZ, Saavedra-Rodriguez K, Penilla-Navarro RP, D. Rodriguez-Ramirez A, Dzul F, Manrique-Saide P, et al. 2020 Loss of pyrethroid resistance in newly established laboratory colonies of Aedes aegypti. PLoS Negl Trop Dis 14(3): e0007753. https://doi.org/10.1371/journal.pntd.0007753

Ordoñez-González JG., Cisneros-Vázquez LA., Danis-Lozano R., Valdez-Delgado, KM., Fernández-Salas I., Penilla-Navarro RP., Saavedra-Rodríguez K., Black IV WC., & Rodríguez AD. 2020. Nebulización térmica intradomiciliar de la mezcla de flupyradifurona y transflutrina en mosquitos Aedes aegypti susceptibles y resistentes a piretroides en el Sur de México [Indoor thermal fogging of the mixture of flupyradifurone and transflutrin on Aedes aegypti mosquitoes susceptible and resistant to pyrethroids in southern Mexico]. Salud pública de Mexico, 10.21149/11142. Advance online publication. https://doi.org/10.21149/11142

2019

Saavedra-Rodriguez K., Campbell CL., Lenhart A., Penilla P., Lozano-Fuentes S. and Black IV WC. 2019. Exome-wide association of deltamethrin resistance in Aedes aegypti from Mexico. Insect Molecular Biology (2019) 1–14  doi: 10.1111/imb.12575

Campbell CL, Saavedra-Rodriguez K, Kubik TD, Lenhart A, Lozano-Fuentes S, Black WC IV. 2019. Vgsc-interacting proteins are genetically associated with pyrethroid resistance in Aedes aegypti. PLoS ONE 14(1): e0211497. https://doi.org/10.1371/journal.pone.0211497

2018

Matthews Benjamin J., Dudchenko Olga, Kingan Sarah B., Koren Sergey, Antoshechkin Igor, Crawford Jacob E., Glassford William J., Herre Margaret, Redmond Seth N., Rose Noah H., Weedall Gareth D., Wu Yang, Batra Sanjit S.,. Brito-Sierra Carlos A, Buckingham Steven D., Campbell Corey L., Chan Saki, Cox Eric, Evans Benjamin R., Fansiri Thanyalak, Filipović Igor, Fontaine Albin, Gloria-Soria Andrea, Hall Richard, Joardar Vinita S., Jones Andrew K., G. G. Kay Raissa, Kodali Vamsi K., Lee Joyce, Lycett Gareth J., Mitchell Sara N., Muehling Jill, Murphy Michael R., Omer, Arina D. Partridge, Frederick A., Peluso Paul, Aiden Aviva Presser, Ramasamy Vidya, Rašić Gordana, Roy Sourav, Saavedra-Rodriguez Karla, Sharan Shruti, Sharma Atashi, Laird Smith Melissa, Turner Joe, Weakley Allison M., Zhao Zhilei, Akbari Omar S., Black IV William C., Cao Han, Darby Alistair C., Hill Catherine A., Johnston J. Spencer, Murphy Terence D., Raikhel Alexander S., Sattelle David B., Sharakhov Igor V., White Bradley J., Zhao Li, Lieberman Aiden Erez, Mann Richard S., Lambrechts Louis, Powell Jeffrey R., Sharakhova Maria V., Tu Zhijian, Robertson Hugh M., McBride Carolyn S., Hastie Alex R., Korlach Jonas, Neafsey Daniel E., Phillippy Adam M. & Vosshall Leslie B.. 2018.  Improved reference genome of Aedes aegypti informs arbovirus vector control. Nature. Volume 563, pages501–507. https://doi.org/10.1038/s41586-018-0692-z

Fernando SD, Hapugoda M, Perera R, Saavedra-Rodriguez K, Black WC 4th, De Silva NK. 2018. First report of V1016G and S989P knockdown resistant (kdr) mutations in pyrethroid-resistant Sri Lankan Aedes aegypti mosquitoes. Parasit Vectors. 2018 Sep 26;11(1):526. doi: 10.1186/s13071-018-3113-0.

Saavedra-Rodriguez Karla, Vera Maloof Farah, Campbell Corey L., Garcia-Rejon Julian, Lenhart Audrey, Penilla Patricia, Rodriguez Americo, Acero Sandoval Arturo, Flores Adriana E., Ponce Gustavo, Lozano Saul & Black William C. 2018. Parallel evolution of vgsc mutations at domains IS6, IIS6 and IIIS6 in pyrethroid resistant Aedes aegypti from Mexico. Sci Rep. 2018 Apr 30;8(1):6747. doi: 10.1038/s41598-018-25222-0.

Loroño-Pino MA, Uitz-Mena A, Carrillo-Solís CM, Zapata-Gil RJ, Camas-Tec DM, Talavera-Aguilar LG, Cetina-Trejo RC, Flores-Flores LF, Puc-Tinal MC, Caamal-Jiménez C, Reyes-Solís G, García-Rejón JE, Saavedra-Rodriguez K, Eisen L, Keefe TJ, Black Iv WC and Beaty BJ. 2018. The Use of Insecticide-Treated Curtains for Control of Aedes aegypti and Dengue Virus Transmission in “Fraccionamiento” Style Houses in México. Journal of Tropical Medicine, vol. 2018, Article ID 4054501, https://doi.org/10.1155/2018/4054501.

2017

Francis S, Saavedra-Rodriguez K, Perera R, Paine M, Black WC IV, Delgoda R. 2017. Insecticide resistance to permethrin and malathion and associated mechanisms in Aedes aegypti mosquitoes from St. Andrew Jamaica. PLoS ONE 12(6): e0179673. https://doi.org/10.1371/journal.pone.0179673

2016

Villanueva OK, Ponce G, Lopez B, Gutierrez S M, Rodriguez I P, Reyes G, Saavedra K, Black IV W C., Garcia J, Beaty B, Eisen L, and Flores A E. 2016.  Effect of photoperiod on permethrin resistance in Aedes aegypti. Journal of the American Mosquito Control Association, 32(4):308-314.

Beaty Barry J., Black IV William C., Eisen Lars, Flores Adriana E., García-Rejón Julián E., Loroño-Pino María and Saavedra-Rodriguez Karla. 2016. The intensifying storm: domestication of Aedes aegypti, urbanization of arboviruses, and emerging insecticide resistance. Global health impacts of vector-borne diseases: workshop summary edited by alison mack rapporteur, forum on microbial threats, board on global health, health and medicine division, National Academies of Sciences, Engineering, Medicine. 04/2016: Chapter 3: pages 111-142; The National Academies Press.

Ponce-García G, Del Río-Galvan S, Barrera R, Saavedra-Rodriguez K, Villanueva-Segura K, Felix G, Amador M, Flores AE. 2016. Knockdown resistance mutations in Aedes aegypti (Diptera: Culicidae) from Puerto Rico. Journal of Medical Entomology, 2016, 1–5  doi: 10.1093/jme/tjw115

2015

Vera-Maloof F, Saavedra-Rodriguez K, Elizondo-Quiroga A, Lozano-Fuentes S, William C. Black IV. 2015. Coevolution of the Ile1,016 and Cys1,534 mutations in the voltage gated sodium channel gene of Aedes aegypti in Mexico.  PloS Negl Trop Dis 9(12) doi:10.1371/journal.pntd.0004263

Denham S, Eisen L, Beaty M, Beaty B, Black IV W, and Saavedra-Rodriguez K. 2015. Two novel bioassays to assess the effects of pyrethroid-treated netting on knockdown susceptible versus resistant strains of Aedes aegypti. Journal of the American Mosquito Control Association 31(1):52-62

Saavedra-Rodriguez K, Beaty M, Lozano-Fuentes S, Denham S, Garcia-Rejon J, Reyes-Solis G, Machain-Williams C, Loroño-Pino MA, Flores AE, Ponce G, Beaty B, Eisen L, and Black IV WC. 2015.  Local evolution of pyrethroid resistance offsets gene flow among Aedes aegypti collections in Yucatan State, Mexico. Am J Trop Med Hyg. 92(1):201-209  doi:10.4269/ajtmh.14-0277

Alvarez L, Ponce G, Saavedra K, Lopez B and Flores A. 2015.  Frequency of V1016I and F1534C mutations in the voltage-gated sodium channel gene in Aedes aegypti of Venezuela. Pest Management Science. doi 10.1002/ps.3846

Capítulos en libros

2016

Barry J. Beaty, William C. Black IV, Lars Eisen, Adriana E. Flores, Julián E. García-Rejón, María Loroño-Pino and Karla Saavedra-Rodriguez. 2016. The Intensifying Storm: domestication of Aedes aegypti, urbanization of arboviruses, and emerging insecticide resistance. Global Health Impacts of Vector-Borne Diseases: Workshop Summary Edited by Alison Mack Rapporteur, Forum on Microbial Threats, Board on Global Health, Health and Medicine Division, National Academies of Sciences, Engineering, Medicine. 04/2016: Chapter 3: pages 111-142; The National Academies Press.

Formación de recursos humanos, tesis dirigidas

2020

Assessing the association between detoxification gene substitutions and insecticide resistance in Aedes aegypti. Tesis para grado de Artes de la estudiante India Hilty. Faculty of Organismal Biology and Ecology, Colorado College, Colorado Springs. Abril 2020.

2018

Niveles de resistencia a insecticidas en Aedes aegypti provenientes de huevos, larvas y adultos colectados en campo. Tesis para obtener el grado de Maestro en Ciencias en Enfermedades Transmitidas por Vector del Bioq. F. Walter Eduardo Quezada Yaguachi. Instituto Nacional De Salud Pública, Escuela De Salud Pública De México

Proyectos de investigación como responsable

2020

Insecticide Resistance Management to Preserve Pyrethroid Susceptibility in Aedes aegypti. National Institutes of Health 5R01AI121211-05