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Dr. José Santos García Alvarado PDF Imprimir E-Mail
escrito por Dr. José Santos García Alvarado   

J. SANTOS GARCIA A.
Professor Level D
Department of Microbiology
Facultad de Ciencias Biológicas
Universidad Autonoma de Nuevo León (UANL)
Monterrey, NL. 66451 Mexico
E-mail: Esta dirección de correo electrónico está protegida contra los robots de spam, necesita tener Javascript activado para poder verla
Webpage: www.microbiosymas.com
Telephone: +52 (81) 83763044; +52 (81) 8329-4110 Ext:6466

EDUCATION
1984 B.S.. Chemist-Bacteriologist-Parasitologist. UANL. México
1990 D.S. Microbiology. UANL. México

ACADEMIC AND PROFESSIONAL APPOINTMENTS:
2007 – to present Professor level D. School of Biological Sciences. UANL Mexico
2001- 2006. Dean. School of Biological Sciences, UANL, Mexico.
1991 - 2000. Chief of Laboratory of Physiology of Microorganisms. School of Biological Sciences, UANL. Mexico
1999- Visiting Scientist. National Animal Disease Center, USDA, Ames, Iowa, USA.
1991- 1999. Visiting Scientist. Food Science Department. University of Massachusetts, USA.
1988 - 1991 Assistant Professor. School of Biological Sciences, UANL. Mexico
1983 - 1991 Research Assistant. School of Biological Sciences, UANL. Mexico
  
RESEARCH INTEREST:

General Area of Research: Physiology, epidemiology and control of foodborne pathogens.


Projects:
1) Epidemiology and control of pathogens in vegetables and meats
2) Antimicrobial activity of natural products against foodborne pathogens
3) Mechanisms of microbial survival.

TEACHING:
1990 – to date. Microbial Physiology. Graduate and undergraduate level.
1196 – to date. Food Microbiology. Graduate Level

EXTENSION:
1992 – to date: Serving the industry and government in laboratory analysis of food microbiology.

GRANTS (CAREER TOTAL)
26 Research Projects as PI or co-PI funded by the Secretary of Education of Mexico, the Mexican National Council of Science and Technology, the U.S. Department of Agriculture, Omnilife Company, 3M Microbiology, the Autonomous University of Nuevo Leon, Biomerieux México and USDA.

AWARDS AND SCIENTIFIC RECOGNITION:
State Health Department Award. State of Nuevo León México. 2003.
Member of the Mexican National Researchers Council. 1992 to date.
Member of the Mexican Academy of Sciences.
Regional Representative of the Latin-American Association for Mycology.
Advisor of the International Foundation for Science, Stockholm, Sweden.
Member of the Editorial Board of Journal of Food Protection.
Member of the Editorial Board of the Internet Journal of Microbiology
Member of the Editorial Board of the International Journal of Agriculture Environment and Biotechnology.
Reviewer of Food Microbiology. Canadian Journal of Microbiology, and others.
Member of H. Junta de Gobierno, Universidad Autonoma de Nuevo Leon. 2008-2019.

MEXICAN FEDERAL RESEARCH PANELS
2000. Member of the international fellowship panel on Microbiology of the Mexican Council for Science and Technology
2002 to date. Member of the Accreditation panel of the Mexican Council for Science and Technology
2003 to 2006. Member of the grant panel on Biotechnology of the Mexican Council for Science and Technology
2006 to 2009. Member of the Advisory Panel of Science and Technology of the Mexican Government
2010-2012. Awards committee member, Mexican Academy of Sciences.

MEMBER OF SCIENTIFIC SOCIETIES
American Society for Microbiology (Since 1991)
International Association for Food Protection
Institute of Food Technologists (Professional member)
Society for General Microbiology
Latin-American Association for Mycology
Mexican Association for Food Science
Association of Microbiologists of India

PUBLICATIONS:

BOOKS.

1.- García Alvarado, J.S. and N. L. Heredia. 1999. Bioquímica y Fisiología de
Microorganismos, Manual de Laboratorio. Universidad Autónoma de Nuevo
León, Facultad de Ciencias Biológicas.  Mexico.

2.- R.G. Labbe and García, S. (Editors). 2001. Guide to Food-borne Pathogens.
John Wiley & Sons. New York. ISBN. 0-471-350346. 404 p.

3.- Dr. Santos García y Dra. Norma Heredia. 2005. Fisiología de
Microorganismos. Manual de Curso. Facultad de Ciencias Biológicas,
Universidad Autónoma de Nuevo León, 84 p. ISBN: 970-694-190-8.

4.- Heredia, N.  y S. García. 2007. Diagnóstico Microbiológico Moderno: Manual
de Laboratorio. UANL. ISBN :978-970-694-443-06.

5.- Norma Heredia, Irene Wesley and Santos García. 2009. Microbiologically
Safe Foods. John Wiley & Sons. New York. ISBN: 9780470053331.

6.- Santos Garcia and Norma Heredia. 2009. Fisología de Microorganismos:
Manual de Laboratorio. Ed. Trillas. Mexico.

CHAPTERS AND PAPERS:
(Reprints of papers can also be requested at: Esta dirección de correo electrónico está protegida contra los robots de spam, necesita tener Javascript activado para poder verla )

1.- Heredia, N.L., R.G. Labbe, M.A. Rodríguez y J.S. García-Alvarado. 1991. Growth, sporulation and enterotoxin production by Clostridium  perfringens type A in the presence of bile salts. FEMS Microbiology Letters, 84: 15-22. Link.

2.- García-Alvarado, J.S., R.G. Labbé y M.A. Rodríguez. 1992. Sporulation and enterotoxin production of Clostridium  perfringens type A at 37 and 43°C. Applied and Enviromental Microbiology, 58(4):1411-1414. Link.

3.- García-Alvarado, J.S., M.A. Rodríguez y R.G. Labbé. 1992. Isolation of inclusion bodies from vegetative Clostridium  perfringens: partial purification of a 47 kDa inclusion protein. Journal of Applied Bacteriology,  73, 157-162. Link.

4.- Labbé, R.G. y J.S. García-Alvarado. 1992. Influence of temperature on sporulation, enterotoxin formation and spore heat resistance of Clostridium perfringens type A. Proc. 3rd World Congress Foodborne Infections and Intoxications, II:1162-1165.

5.- Heredia, N.L., J.S. García-Alvarado y M.A. Rodríguez. 1992. Técnica inmunoenzimática rápida de tipo "ELISA" para la detección de enterotoxina de Clostridium  perfringens tipo A. Publicaciones Biológicas, 6(2) :139-141.

6.- García-Alvarado, J.S. Manuel A. Rodríguez, and Ronald G. Labbé. 1992. Influence of Elevated Temperature on Starch Hydrolysis by Enterotoxin-Positive and Enterotoxin-Negative Strains of Clostridium perfringens Type A. Applied and Environmental Microbiology 58(1) p. 326-330. Link.

7.- Heredia, N.L., J.S. García-Alvarado, y R.G. Labbé. 1994. Improved rapid method for production and purification of Clostridium perfringens type A enterotoxin.  Journal of Microbiological Methods, 20:87-91. Link.

8.- Castro-Franco, R., J.S. García-Alvarado, L.J. Galán-Wong y A. Gallegos-del-Tejo. 1995. Efecto sinérgico de extractos de bagazo de Agave lechuguilla Torr. en la actividad insecticida de Bacillus thuringiensis contra Spodoptera frugiperda Smith. PHYTON, International Journal of Experimental Botany, 57 (2):113-119.

9.- Verastegui, M.A., C.A Sánchez-García, N.L. Heredia y J.S. García-Alvarado. 1996. Antimicrobial activity of three major plants of the Chihuahuan desert. Journal of Etnopharmacology, 52: 175-177. Link.

10.- Heredia, N.L., G. A. García, R. Luévanos, J.S. García-Alvarado y R. G. Labbé. 1997. Elevation of the heat resistance of vegetative cells and spores of Clostridium perfringens by sublethal heat shock. Journal of Food Protection, 60(8): 998-1000. Link.

11.- Rodríguez-Romo, L.A., N.L. Heredia, R.L. Labbé y J.S. García-Alvarado. 1997. Detection of enterotoxigenic Clostridium perfringens in spices used in México by dot blotting using a DNA probe. Journal of Food Protection, 61(2):201-204. Link.

12.- Castro-Franco, R., J. S. García Alvarado and L. J. Galan-Wong.1998. An alternative bioinsecticide formulation to encapsulate Bacillus thuringiensis d-toxin and extracts of Agave lecheguilla Torr. for the control of Spodoptera frugiperda Smith. PHYTON, International Journal of Experimental Botany, 62(1/2): 71-77.

13.- Heredia, N.L., J.S. García-Alvarado y R. G. Labbé. 1998. Alteration in sporulation, enterotoxin production and protein synthesis by Clostridium perfringens type A following heat shock. Journal of Food Protection, 61(9):1143-1147. Link.

14.- Maiti, R.K., A. Reyes-García, N.L. Heredia, H. Gómez and J.S. García-Alvarado. 1998. Comparison of the protein profiles of four genotypes of “glossy” sorghum subjected to salinity at seedling stage. International Sorghum and Millets Newsletter, 39: 101-103. Link.

15.- Vela, M., N.L. Heredia, P. Feng, and. J.S. García Alvarado. 1999. DNA probe analysis for the carriage of enterotoxigenic Clostridium perfringens in feces of a Mexican subpopulation. Diagnostic Microbiology and Infectious Disease, 35(2): 101-104. Link.

16.- N.L. Heredia y J.S. García Alvarado. 1999. Clostridium perfringens. In  Torres-Vitela, R. (Ed). Agentes Patógenos Transmitidos por Alimentos. Universidad Autónoma de Guadalajara. pp159-169.

17.- S.J. Martínez, J.S. García, N.L. Heredia, L. Villarreal  and C. García. 2000. Antifungal activity of extract of Sargassum filipendula. PHYTON, International Journal of Experimental Botany. 66: 179-182.

18.- Villarreal, L., N.L. Heredia and J.S. García-Alvarado. 2000. Changes in protein synthesis and acid tolerance of Clostridium perfringens type A as a result of an acid shock. International Microbiology 3(2): 113-116. Link.

19.- Castro, R., S. García and L. Galán. 2000. Aportaciones de la Biotecnología de formulados a base de Bacillus thuringiensis para el control de plagas agrícolas. In: Pedroza, A, J.H. Esparza y Ruiz, J. Aprovechamiento integral de los recursos naturales en zonas áridas.  Universidad Autónoma de Chapingo, Bermejillo, Dgo. México. p. 71-87.

20.- García-Alvarado, J. S. M. J. Verde-Star and N. L. Heredia. 2001. Traditional uses and scientific knowledge of medicinal plants from Mexico and Central America. A review. Journal of Herbs Spices and Medicinal Plants, 8 (2/3): 37-89. Link.

21.- Castro, R., C. Meza, M. Lechuga y S. García. 2000. Desarrollo de un medio de cultivo para la propagación de esporas de hongos enteropatógenos. Revista Chapingo, serie Zonas Áridas. 1(2): 79-84.

22.- García, S., F. Iracheta, F. Galván and N.L. Heredia. 2000. Microbiological survey of retail herbs and spices from Mexican markets. Journal of Food Protection. 64(1): 99-103. Link.

23.- Limón, J.C., N.L. Heredia, y J.S. García Alvarado. 2001. Cross protection by heat and cold shock to sublethal temperatures in Clostridium perfringens. Brazilian Journal of Microbiology. 32: 110-112. Link.

24.- Wesche-Ebeling, P.,  R.K. Maiti, J.S García-Alvarado and N.L. Heredia. 2002. Food and Feed Science. In Maiti, R. and P. Wesche (Ed). Peanut Science. Oxford nd IBH Publishing CO. PVT. LTD. New Delhi, India. 243-283.

25.- Fernández-Escartín, E. and J.S. García. 2001. Miscellaneous agents: Brucella, Aeromonas, Plesiomonas, and b-hemolytic streptococci. In García, J.S. and R.G. Labbé (Ed) Guide to Food-borne Pathogens. John Wiley and Sons. New York. 295-313.

26.- Bathnagar, D. and J.S. García Alvarado.2001. Aspergillus. In García, J.S. and R.G. Labbé (Ed) Guide to Food-borne Pathogens. John Wiley and Sons. New York. pp. 35-50.

27.- Heredia, N.L., S. García, G. Rojas and L. Salazar. 2001. Microbiological condition of  ground   meat  retailed in Monterrey, Mexico. Journal of Food Protection. 64(8): 1249-1251. Link.

28.- Castro, R., C. Meza, M. Contreras and S. García. 2001. Uso de fitoextractos en el control del crecimiento In Vitro de bacterias enteropatógenas. Revista Chapingo, serie Zonas Áridas. 2(1): 96-99.

29.- Villarreal, L.,  N.L. Heredia and S. García. 2002. Cold tolerance and changes in rates of synthesis of individual proteins of Clostridium perfringens as a result of cold pre-treatment. Acta Alimentaria 31: (2)179-184. Link.

30.- Martínez, S., N. Heredia, S. García, S. Moreno, J. Guevara, A. Núñez, L. Cárdenas. 2002. Efecto del extracto de Ulva fasciata (Chlorophyta)  sobre el crecimiento bacteriano y fúngico. PHYTON, International Journal of Experimental Botany. 2001: 163-166. Link

31.- Garcia S., M. Araiza; M. Gomez, N. Heredia. 2002. Inhibition  of  growth,  enterotoxin  production, and spore formation of  Clostridium  perfringens by extracts of medicinal plants. Journal of Food Protection. 65(10):1667-1669. Link.

32.- Valdés-Taméz, V., Foroughbakhch P R., Treviño-Garza, E.J., García-Alvarado, J.S., Alanís-Flores, G.J., Alvarado-Vázquez, M.A. y Jurado-Y, E. 2002. Flora medicinal del municipio de Santiago, Nuevo León, México. Su importancia y distribución en la vegetación. PHYTON, International Journal of Experimental Botany.  2002:173-179.

33.- Heredia, N.L., E. Aréchiga, R.G. Labbé, R.G. and  S. García. 2003. Stress proteins of Clostridium perfringens type A immunoreact with antiserum from rabbits infected with gas gangrene. International Microbiology. 6:259-261. Link.

34.- Álvarez, G., N.L. Heredia and S. García. 2003. Relationship between the effects of stress induced by human bile juice and acid treatment in Vibrio cholerae. Journal of Food Protection.  66: 2283-2288. Link.

35.- N. Heredia y S. García. 2004. Métodos Rápidos de Diagnóstico. Manual para el Diagnóstico de Patógenos en Lácteos y Carnes Mediante PCR. Folleto Técnico No. 5 INIFAP. Págs. 29-33. México. ISBN 1405-1915.

36.- García, S., G. Alarcón, M. Gómez and N. Heredia. 2005. Haematoxylon brasiletto extracts inhibit growth, enterotoxin production, and adhesion of Vibrio cholerae. Food Biotechnology. 19: 15-26. Link.

37.- Sanchez, E., N. Heredia and S. García. 2005. Inhibition of growth and mycotoxin production of Aspergillus flavus and Aspergillus parasiticus by extracts of Agave species. International Journal of Food Microbiology. 98:271-279. USA. Link.

38.- Heredia, N., M. Escobar, C. Rodriguez and S. García. 2005. Extracts of Haematoxylon brasiletto inhibit growth, verotoxin production, and adhesion of enterohemorragic Escherichia coli O157:H7 to HeLa cells. Journal of Food Protection. 68:1346-1351. USA. Link.

39.- García, S. and N. Heredia. 2006. Mycotoxins in Mexico: Epidemiology, management, and control strategies. Mycopathologia. 162:255-264. Link.

40.- García, S., Alarcón, G., Rodríguez, C. And Heredia, N. 2006. Extracts of Acacia farnesiana and Artemisia ludoviciana inhibit growth, enterotoxin production and adhesion of Vibrio cholerae. World Journal of Microbology & Biotechnology, 22:669-674. Link.

41.- Garcia S. and N. Heredia. 2009. Overview of foodborne pathogens. In: Heredia, N., I Wesley and S. Garcia (Eds). Microbiologically Safe Foods. John Wiley and Sons. New York.

42.- Heredia, N. and S. Garcia. 2009. Microbiology of chocolate and sweeteners. In: Heredia, N., I Wesley and S. Garcia (Eds). Microbiologically Safe Foods. John Wiley and Sons. New York.

43.- Sanchez, E., L. Solis, S. Garcia and N. Heredia. 2009. Traditional methods of diagnostic. In: Heredia, N., I Wesley and S. Garcia (Eds). Microbiologically Safe Foods. John Wiley and Sons. New York.

44.- Verastegui, A., S. García, A. Oranday, C. Rivas and N. Heredia. 2008. Species of Agave with antimicrobial activity against selected pathogenic bacteria and fungi. World Journal of Microbiology & Biotechnology. 24:1249-1252. Link.

45.- Heredia, N., Ybarra, P., Hernández C. and García, S. 2008. Extracellular protectants produced by Clostridium perfringens cells at elevated temperatures. Letters in Applied microbiology. 48 (1):133-139. Link.

46.- Ramirez, R., Y. Almanza, S. García and N. Heredia. 2009. Adherence and invasion of avian pathogenic Escherichia coli to avian traqueal cells. World J. Microbiology and Biotechnology. 25:1019-1023. Link.

47.- Ramírez, R., Almanza, Y., González R., García, S., and Heredia., N.L. 2009. Avian pathogenic Escherichia coli binds fibronectin and laminin. Veterinary Research Communications. 33:379-386. DOI: 10.1007/s11259-008-9180-5. Link.

48.- García, S., and N. Heredia. Clostridium perfringens: A dynamic foodborne pathogen. Food and Bioprocess Technologies. DOI: 10.1007/s11947-009-0182-2. Link.

49.-   Valtierra-Rodríguez, Diana, Heredia N.L., García, S. and Sánchez E. 2010. Reduction of Campylobacter jejuni and Campylobacter coli in poultry skin by fruit extracts. Journal of Food Protection. 73:477-482. Link.

50.- Limon JC, L. Solís, S. García, and N. Heredia. GRAS substances induced cold tolerance in Clostridium perfringens. Acta Alimentaria, Submitted.

51.- Malagón,  I., García, S. and Heredia N. Virulence factors of Mexican wild-type strains of Campylobacter coli and Campylobacter jejuni. Journal of Food Protection. In press.

52.-  Rosas-Taraco, A., E. Sanchez, N. Heredia,  D. Bhatnagar and S. García. Extracts of Agave americana demonstrate activities against conidiogenesis and aflatoxin production of Aspergillus parasiticus. World Mycotoxin Journal. In press.

53.- Sánchez, E., S. García, and N Heredia. Extracts of edible and medicinal plants damage membranes of Vibrio cholerae. Applied and Environmental Microbiology. Accepted 2010.

54.- Solís-Soto, LY, S. García, I. Wesley and N. Heredia. A charcoal- and blood-free enrichment broth for isolation and PCR detection of Campylobacter jejuni and Campylobacter coli. Submited

55.- Castillo, S.L., N. Heredia, J.F. Contreras and S. García. Mexican plant extracts against Campylobacter jejuni and Campylobacter coli: effect in growth, adherence and cytotoxic activity. In preparation

56.- Solís, L.Y., N. Heredia and S. García. Extracellular compounds of Bacillus cereus with thermoprotective action on non-stressed cells. In preparation.

57.- Fernandez, F.M., N.L. Heredia, and S. Garcia. Inhibition of growth of species of Listeria ssp.  by Mexican medicinal plants. In preparation.

58.- Lozano-Muñiz, S., S. García, N. Heredia and R. Castro-Franco. Species of Agave induced morphological changes on Aspergillus parasiticus Speare and Aspergillus flavus Link Ex Fries In preparation.

 

Modificado el ( Thursday, 24 de February de 2011 )