NORMA HEREDIA
Professor Level D
Department of Microbiology
Facultad de Ciencias Biológicas
Universidad Autonoma de Nuevo León (UANL)
Monterrey, NL. 66451 Mexico
EDUCATION:
1988 B.Sc. Chemist-Bacteriologist-Parasitologist. (Microbiology) Univ. A. de Nuevo León. México
1991 Master of Science. Medical Microbiology. Univ. A. de Nuevo León. México
1996 Doctor of Science. Microbiology. Univ. A. de Nuevo León. México
1989 - 1999. Visiting Scientist. Food Science Department. University of Massachusetts,
1999 - Visiting Scientist. National Animal Disease Center, USDA, Ames, Iowa, E.U.A.
PROFESIONAL EXPERIENCE:
1990 - 1996 Research Assistant. School of Biological Sciences, UANL.
1996- 2003 Assistant Professor. School of Biological Sciences, UANL.
2003- to present Professor Level B. School of Biological Sciences, UANL.
2004. Chief of Laboratory of Physiology of Microorganisms. School of Biological Sciences
RESEARCH INTEREST:
1) Bacterial toxins and enzymes, in particular of C. perfringens, V. cholerae and other foodborne pathogens.
2) Activity of natural products from plants and microbes against food-borne pathogens.
3) Classic and molecular epidemiology of foodborne pathogens.
Keywords: C. perfringens,V. cholerae, Campylobacter, natural products, stress response
CURRENT RESEARCH COLABORATIONS IN THE USA:
Ronald Labbé. University of Massachusetts, Amherst, MA. USA.
Irene Wesley, National Animal Diseases Center, USDA, Ames IA. USA.
Mark Tamplin, University of Tasmania, Australia.
Juan Leon, Emory University
LeeAnn Jaykus, North Carolina State Unioversity
TEACHING:
Food Safety and Microbial Physiology. Undergraduate and Graduate level.
Quality Control Systems. Graduate level
Modern Diagnostic Microbiology. Undergraduate level.
EXTENSION:
1992 – to date: Serving the industry and government in laboratory analysis of food microbiology.
AWARDS AND SCIENTIFIC RECOGNITION:
State Health Department Award. State of Nuevo León México. 2003.
Member of the Mexican National Researchers Council. 1992 to date.
Member of the Mexican Academy of Sciences.
Advisor of the International Foundation for Science, Stockholm, Sweden.
Member of the Editorial Board of Journal of Food Protection.
Reviewer of Food Microbiology. Journal of the Science of Food and Agriculture, and others.
Pathogenesis, World Journal of Microbiology and Biotechnology and others.
MEMBER OF SCIENTIFIC SOCIETIES
American Society for Microbiology (Since 1992)
International Association for Food Protection
Mexican Association for Food Protection
Mexican Association for Microbiology
GRANTS (CAREER TOTAL)
25 Research Projects as PI or co-PI funded by the Secretary of Education of Mexico, the Mexican National Council of Science and Technology, the U.S. Department of Agriculture, Omnilife Company, 3M Microbiology, Biomerieux Company, and the Autonomous University of Nuevo Leon.
PUBLICATIONS:
Peer-Reviewed Papers and books (published, in press, accepted, or submitted, career total of 53):
Books:
1.- Heredia, N. and S. Garcia. 2005. Physiology of Microorganisms, a laboratory manual (in Spanish). UANL. Monterrey.
2.- Heredia, N. y S. García. 2007. Modern Diagnostic Microbiological Methods: a laboratory manual (in Spanish). UANL. Monterrey.
3.- Heredia, N., I. Wesley and S. Garcia. 2008. Microbiologically Safe Foods. John Wiley and Sons. New York. Accepted.
Papers in Journals:
1.- Heredia, N.L., R.G. Labbe, M.A. Rodriguez, and J.S. Garcia-Alvarado. 1991. Growth, sporulation and enterotoxin production by Clostridium perfringens type A in the presence of bile salts. FEMS Microbiology Letters, 84: 15-22
2.- Heredia, N.L., J.S. García-Alvarado y M.A. Rodríguez. 1992. Técnica inmunoenzimática rápida de tipo "ELISA" para la detección de enterotoxina de Clostridium perfringens tipo A. Publicaciones Biológicas, 6(2) :139-141.
3.- Heredia, N.L., J.S. García-Alvarado, y R.G. Labbe. 1994. Improved rapid method for production and purification ofClostridium perfringens type A enterotoxin. Journal of Microbiological Methods, 20:87-91.
4.- Verástegui, M.A., C.A Sánchez-García, N.L. Heredia y J.S. García-Alvarado. 1996. Antimicrobial activity of three major plants of the chihuahuan desert. J. Etnopharmacology, 52: 175-177.
5.- Heredia, N.L., G. A. García, R. Luévanos, J.S. García-Alvarado y R. G. Labbé. 1997. Elevation of the heat resistance of vegetative cells and spores of Clostridium perfringens by sublethal heat shock. J. Food Protec. 60(8): 998-1000.
6.- Rodríguez-Romo, L.A., N.L. Heredia, R.L. Labbé y J.S. García-Alvarado. 1998. Detection of enterotoxigenicClostridium perfringens in spices used in México by dot blotting using a DNA probe. J. Food Protect. 61(2): 201-204
7.- Wesche-Ebeling, P., N.L. Heredia y R.K. Maiti. 1998. Biotechnology. IN Maize Science Vol II. Science publishers., Inc. New Hampsire, E.U.A. pp. 339-399
8.- Heredia, N.L., J.S. García-Alvarado y R. G. Labbé. 1998. Alteration in sporulation, enterotoxin production and protein synthesis by Clostridium perfringens type A following heat shock. J. Food Prot. 61(9): 1143-1149
9.- Maiti, R.K., A. Reyes-García, N.L. Heredia, H. Gómez and J.S. García-Alvarado. 1998. Comparision of the protein profiles of four genotypes of “glossy” sorghum subjected to salinity at seedling stage. Int. Sorghum and Millets Newsletter 39: 101-103
10.- Vela, M., N.L. Heredia, P. Feng and J.S. García-Alvarado. 1999. DNA probe analysis for the carriage of enterotoxigenic Clostridium perfringens in feces of a Mexican subpopulation. Diagnostic Microbiol and Infec Dis. 35: 101-104.
11.- N.L. Heredia y J.S. García Alvarado. 1999. Clostridium perfringens. In Torres-Vitela, R. (Ed). Agentes Patógenos Transmitidos por Alimentos. Universidad Autónoma de Guadalajara. Pp. 159-173
12.- S.J. Martínez, J.S. García, N.L. Heredia, L. Villarreal and C. García. 2000. Extract of Sargassum filipendulaexhibits antifungal activity. Phyton, International Journal of Experimental Botany. 66: 179-182
13.- Villarreal, L., N.L. Heredia y J.S. García-Alvarado. 2000. Changes in protein synthesis and acid tolerance ofClostridium perfringens type A as a result of an acid shock. International Microbiology. 3: 113-116.
14.- J.S. García, F. Iracheta, F. Galván and N.L. Heredia. 2001. Microbiological survey of retail herbs and spices from Mexican markets. Journal of Food Protection. 64(1): 99-104
15.- Heredia, N.L., S. García, G. Rojas and L. Salazar. 2001. Microbiological status of retailed ground meat in the metropolitan area of Monterrey, México. Journal of Food Protection. 64: 1249.1251.
16.- García-Alvarado, J.S., M.J. Verde-Star and N.L. Heredia. 2001. Traditional Uses and scientific knowledge of medicinal plants from Mexico and Central America.A review. Journal of Herbs Spices and Medicinal Plants. 8(2/3): 37-89.
17.- Limón, J.C., N.L. Heredia, y J.S. García Alvarado. 2001. Cross protection by heat and cold shock to sublethal temperatures in Clostridium perfringens. Brazilian Journal of Microbiology.32: 110-112
18.- A. Nuñez, R. Maiti, R. Foroughbakch, G. García, S. Martínez, N. Heredia, S. Moreno, J. Hernandez and M. Cárdenas. 2001. Genotypic variability in adsorption of minerals among bean (Phaseolus vulgaris I.) cultivars exposed to low nutrient stress. Crop Research. 22(3): 408-423.
19.-. A. Núñez, N.L. Heredia, R. Maiti, J.Verde, S. Moreno, G. Alvarez, M. Cárdenas and J. Hernández. 2001. Comparision of the protein porfiles of four bean cultivars (Phaseolus vulgaris) subjected to low nutrient level: a preliminary study. Legume Research. 24: 130-132
21.- Villarreal, L., N. L. Heredia and S. García. 2002. Cold tolerance and changes in rates of synthesis of individual proteins of Clostridium perfringens as a result of cold pre-treatment. Acta Alimentaria 31: 179-184.
22.- A. Nuñez, R. Maiti, N. Heredia, J. Verde, R. Foroughbackch, S. Martínez, S. Moreno, G. García, M. Cárdenas and J. Hernández. 2002. Characterization of proline, chlorophyll content and protein porfile of bean (Phaseolus vulgaris) cultivars tolerant and susceptible to low nutrient conditions. Phyton, International Journal of Experimental Botany. 2002: 149-155
23.- Martinez, S., N. Heredia, S. García, S. Moreno, J. Guevara, A. Núñez, L. Cárdenas. 2002. Efecto del extracto deUlva fasciata (Chlorophyta) sobre el crecimiento bacteriano y fúngico. Phyton, International Journal of Experimental Botany. 2001:163-166.
24.- S. Garcia, M. Araiza, M. Gómez and N. Heredia. 2002. Inhibition of Growth, Enterotoxin and Spore Production ofClostridium perfringens by Extracts of Medicinal Plants. Journal of Food Protection. 65: 1667-1669.
25.- Heredia, N.L., E. Aréchiga, R.G. Labbé, R.G. and J.S. García. 2003. Stress proteins of Clostridium perfringenstype A immunoreact with antiserum from rabbits infectd with gas gangrene. International Microbiology. 6: 259-261
26.- Alvarez, G., N.L. Heredia and S. García. 2003. Relationship between stress response towards human bile juice and acid treatment in Vibrio cholerae. Journal of Food Protection. 66: 2283-2288.
27.- Sánchez, E., N. Heredia and S. García. 2005. Inhibition of growth and mycotoxin production of Aspergillus flavusand Aspergillus parasiticus by extracts of Agave species. International Journal of Food Microbiology 98: 271-279.
28.- García, S., G. Alarcón, M. Gómez and N. Heredia. 2005. Haematoxylon brasiletto extracts inhibit growth, enterotoxin production and adhesion of Vibrio cholerae. Food Biotechnology. 19(1): 15-26
29.- Heredia, N., M. Escobar, C. Rodriguez and S. García. 2005. Extracts of Haematoxylon brasiletto inhibit growth, verotoxin production, and adhesion of enterohemorragic E. coli O157:H7 to HeLa cells. Journal of Food Protection. 68: 1346-1351
30.- García, S., Alarcón, G., Rodriguez, C. and Heredia, N. 2006. Extracts of Acacia farnesiana and Artemisia ludoviciana inhibit growth, enterotoxin production and adhesion of Vibrio cholerae. World Journal of Microbiology & Biotechnology. 22(7): 669-674
31.- García, S. and N. Heredia. 2006. Mycotoxins in Mexico: Epidemiology, management, and control strategies. Mycopathologia. 162:255-264
32.- Zúñiga-Estrada, A., F. Tejeda-Trujillo, F. Concha Valdez and N. Heredia. 2006. Microbiología Sanitaria. Revista Latinoamericana de Microbiología. 48(2): 226-230
33.- Mercado, D., R. Belmares, A. Aguilera-Cabo, J.C. Contreras-Esquivel, R. Rodríguez, N. Heredia and C. Aguilar. 2007. Toxicity and In vitro digestability of creosote brush and tar bush fermented under fungal solid state culture conditions. Res. J. Biol. Sci. 2(5): 571-575
34.- Verastegui, A., S. García, A. Oranday, C. Rivas and N. Heredia. 2008. Species of Agave with antimicrobial activity against selected pathogenic bacteria and fungi. World Journal of Microbiology & Biotechnology. 24:1249-1252.
35.- Heredia, N., Ybarra, P., Hernández C. and García, S. 2009. Extracellular protectants produced by Clostridium perfringens cells at elevated temperatures. Letters in Applied Microbiology. 48: 133-139.
36.- Ramirez, R., Y. Almanza, S. Garcia and N. Heredia. 2009. Avian pathogenic Escherichia coli bind fibronectin and laminin. Veterinary Research Communications. In press.
37.- Ramirez, R., Y. Almanza, S. García and N. Heredia. 2009. Adherence and invasion of avian pathogenicEscherichia coli to avian traqueal epithelial cells. World Journal of Microbiology & Biotechnology. 25:1019-1023.
38.- García S. and N. Heredia. 2009. Clostridium perfringens: A dynamic foodborne pathogen. Food and Bioprocess Technology: An International Journal. In press.
39.- Valtierra, D., N. Heredia, E. Sanchez and S. García. 2010. Reduction of Campyobacter jejuni/coli in poultry skin by fruit extracts. Journal of Food Protection. 73: 477-482.
40.- García, S., J. Limón, Y. Solis and N. Heredia. 2010. Cold tolerance of Clostridium perfringens induced by GRAS substances. Acta Alimentaria. Aceptado.
41.- Malagón, I., S. García and N. Heredia. 2010. Virulence factors of Mexican wild-type strains of Campylobacter coliand Campylobacter jejuni. J. Food Prot. Aceptado.
42.- Rosas-Taraco, A., S. García, N. Heredia, E. Sanchez, D. Bhatnagar, A. Morales-Loredo, S. Lozano. 2010. Extracts of Agave americana inhibit aflatoxin production in Aspergillus parasiticus. World Mycotoxin Journal. Aceptado.
Chapters in books:
1.- Heredia, N.L. and R.G. Labbé. 2001. Clostridium perfringens IN J.S. García-Alvarado and R.G. Labbé (Ed). Guide to Foodborne Pathogens. John Wiley & Sons. pp. 133-142.
2.- Wesche-Ebeling, P., R.K. Maiti, J.S García-Alvarado and N.L. Heredia. 2002. Food and Feed Science. IN The Peanut (Arachis hypogaea) Crop. Science Publishers, Inc. Enfiels, NH.
3.- Heredia, N.L. y S. Garcia. 2004. Métodos rápidos de diagnóstico. In Morales, A., I.O Martínez, G.Alvarez and S. Lozano (Eds). Manual para el diagnóstico de patógenos en lácteos y carnes mediante PCR. Editado por el Inifap. ISSN 1405-1915. pp. 29-33
4.- Garcia S. and N. Heredia. 2009. Overwiew of foodborne pathogens and toxins. In: Heredia, N., I Wesley and S. Garcia (Eds). Producing Microbiologically Safe Foods. John Wiley and Sons. New York. In press.
5.- Heredia, N. and S. Garcia. 2009. Microbiology of chocolate and sweeteners. In: Heredia, N., I Wesley and S. Garcia (Eds). Producing Microbiologically Safe Foods. John Wiley and Sons. New York. In press.
6.- Feng, P. and N. Heredia. 2009. Rapid methods for foodborne bacterial enumeration and pathogen detection. In: Heredia, N., I Wesley and S. Garcia (Eds). Producing Microbiologically Safe Foods. John Wiley and Sons. New York. In press.
7.- Sanchez, E., L. Solis, S. Garcia and N. Heredia. 2009. Traditional methods of diagnostic. In: Heredia, N., I Wesley and S. Garcia (Eds). Producing Microbiologically Safe Foods. John Wiley and Sons. New York. In press.
8.- Heredia, N.L. and S. García. 2010. Detección rápida de patógenos y toxinas en Alimentos: pros y contras. Avances en Proteómica del Siglo XXI. Universidad Autónoma de Durango.
Difussion papers:
1.- González Martínez, B.E., Jimenez Salas, Z., Heredia Rojas, N.L. Villarreal Treviño, L., García Díaz, G. y Gómez Treviño, M. 2006. Efecto de microorganismos probióticos sobre el crecimiento de Salmonella enteritidis var. Typhimurium. Ciencia UANL, Vol. IX (4): 365-374
2.- Norma Heredia. 2007. Alimentos seguros, protagonistas clave en el Congreso Inocuidad Alimentaria de la UANL. Industria Alimentaria. Enero-Febrero 2007.
PAPERS IN MEETINGS:
Internacional 160, Mexican 108.
ADVISOR
5 ScD. students,
27 M.Sc students
22 B.Sc. students
